- sesame oil is so helpful and delicious in foods because of its fatty acid content. Sesame oil contains a wide range of polyunsaturated fatty acids, including sesamol and sesamein. This can keep the cardiovascular system balanced and keeps cholesterol levels low. It can also drop the cholesterol levels that the body already has, thereby reducing atherosclerosis. This means that you are better protected from heart attacks and strokes if you add sesame oil to your diet.